Biological and Medical Sciences

Medical and Biological sciences

group of 116 women for comparison has daughters with physiological flowing of pubescence period. The age of first menstruation and a character of the beginning of the women’s menstrual function in the comparative groups aren’t greatly different. Real difference in the clinic demonstration of diseases of ears, noses, threats organs 57(49,1%) the daughters have their broken menstrual function and...

Medical and Biological sciences

BIOLOGICAL SCIENCES: Medical Sciences Pathogenetic mechanisms of AA amyloidosis Short title: Pathogenesis of AA amyloidosis

a Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London NW3 2PF, UK; b Centre for Biomedical Science, Division of Medicine, University College London, London NW3 2PF, UK; Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy; d Centre for Neuroendocrinology, Division of Medicine, University Colle...

BIOLOGICAL SCIENCES: Medical Sciences The mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy

A hypoxic microenvironment induces resistance to alkylating agents by activating targets in the mammalian target of rapamycin (mTOR) pathway. The molecular mechanisms involved in this mTOR-mediated hypoxia-induced chemoresistance, however, are unclear. Here we identify the mTOR target N-myc downstream regulated gene 1 (NDRG1) as a key determinant of resistance toward alkylating chemotherapy, dr...

Yoga and medical sciences.

The ultimate aim of medical sciences is the attainment of optimum physical and mental health for the individual. The ultimate aim of yogic practices is also the same, viz. physical and ll;lental well-being. The difference, however, lies in the use of different methodologies and modalities to achieve those ends. During recent years there has been world-wide interest in yoga. Scientists have been...